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Tert-butyl acetate production method
Apr 25, 2018

1.Acetic anhydride method: Tert-butyl alcohol, acetic anhydride and anhydrous zinc chloride are mixed and heated to reflux for 2 h, then cooled, distilled to a temperature of 110° C., the crude oil is washed with water, and washed with 10% potassium carbonate to neutrality. , Drying with anhydrous potassium carbonate, and then distillation, collecting 95-96 ° C distillate derived products.

2. Acetyl chloride method Mix tert-butanol, N,N-dimethylaniline and anhydrous ether, heat reflux, add acetyl chloride, control feed temperature, maintain moderate reflux speed, add 2/3 acetyl chloride, N The crystals of N-dimethylaniline hydrochloride were cooled in an ice bath and then heated for 1 h. Water was added to dissolve all solids, the ether layer was separated, extracted with cold 10% sulfuric acid, washed with saturated sodium bicarbonate solution once, dried over anhydrous sodium sulfate, and fractionally distilled to obtain a finished product.

3. Acetyl chloride-magnesium method Mix magnesium powder, tert-butanol and anhydrous ether, add acetyl chloride and anhydrous ether solution, add cooling, add cold potassium carbonate solution to decompose, and extract three times with ether. Calcium chloride drying, distillation derived products. Solvents, gasoline anti-seismic agents, nitrocellulose and other solvents.