The solvent is the most important use of dichloromethane. Dichloromethane has a strong dissolving power, a low boiling point and a relatively lowest toxicity and relatively best reaction inertness, making it the first organic solvent to be used in organic synthesis. As a solvent, its status is almost equal to that of inorganic salt chemistry. It is widely used in the manufacture of security film and polycarbonate, and the rest are used as coating solvents, metal degreasers, gas aerosol propellants, polyurethane foaming agents, mold release agents, and paint strippers.
In the pharmaceutical industry as a reaction medium for the preparation of ampicillin, hydroxy benzyl penicillin and cephalosporin, etc.; also used as a solvent in film production, petroleum dewaxing solvents, aerosol propellants, organic synthetic extractants, polyurethane foam Plastic production foaming agents and metal cleaning agents.
Dichloromethane appears to be inert due to the three-dimensional electron effect and usually does not participate in chemical reactions. However, it can also participate in the reaction under certain conditions. There have been industrial accidents where residual methylene chloride and sodium azide reacted in N,N-dimethylformamide to form diazide and the plant was blown off.
Dichloromethane is mainly used in film production and medicine in China. Among them, consumption for film production accounts for 50% of total consumption, medicine accounts for 20% of total consumption, consumption of detergents and chemical industry accounts for 20% of total consumption, and other aspects account for 10%.